hybrid embryo noun2 •An embryo resulting from the sperm of one species fertilising the egg of another.True hybrid embryos are the result of fertilising an egg with the sperm of another closely related species; for example, a mule is the hybrid offspring of a donkey and a horse. — 2008 •Specifically, an embryo created artificially which combines human and animal DNA, in various proportions, for the purposes of medical research. formshybrid embryos