hot tamale noun 2exclamation 1forms 1 noun2 •(US, informal) A physically attractive person."Isn't he the cutest thing?" she whispered to Evelyn. "Have you noticed? This place is absolutely crawling with gorgeous men. The ticket-taker, that Latin hot tamale […]" — 1978 •(US, informal) A comical person or thing.He' so funny; what a hot tamale he is! exclamation1 •An exclamation of surprise.Boy oh boy it’s cold today, hot tamale! formshot tamales