homoousian /hɒməʊˈuːzɪən/adjective 1noun 1forms 1 adjective1 •Having the same essence or substance, especially with reference to the first and second persons of the Trinity (Father and Son). noun1 •(historical) One of those, in the 4th century, who accepted the Nicene Creed and maintained that the Son had the same essence or substance with the Father. formshomoousians