hit up verb 5noun 1forms 4 verb5 •(informal) To visit with or contact someone, especially with a definite purpose.Why not hit him up for some assistance on the rebuilding project? •(slang) To request or demand; to confront verbally.He hit me up for twenty bucks. •To embark on or devote oneself to (an activity); to perform or do (something).I hit up the computer to find the answer. •(informal) To take (an intoxicating drug).He hit up with the heroin Jake brought him. •To eat or drink; to buy a round of drinks.Jerry will hit up a round for us all. noun1 •The act of taking a pass from the dummy half and running straight into the opposition's defensive line without looking to pass. formshitting up · hits up · hit ups · hit-ups