high fructose corn syrup noun1 •(US) A type of corn syrup that has undergone an enzymatic processing to convert some of its glucose into fructose in order to produce a desired sweetness.In 1982, high fructose corn syrup production amounted to 8.4 billion pounds with a value well in excess of one billion dollars. — 2005 formshigh fructose corn syrups · high-fructose corn syrups