hands off exclamation 2adjective 1forms 2 exclamation2 •(informal) Refrain from touching; refrain from initiating any physical contact. •(historical) Cut off a hand: decreed by old admiralty law as punishment for pulling a knife during a fight with a shipmate. adjective1 •Tending not to interfere with the decisions and actions of other people (employees, subjects, etc.). formsmore hands off · most hands off