fatten up verb3 •To cause to gain weight by means of feeding.My cat looks underweight, so I'll fatten him up with higher-calorie cat food.I visited my mother for a month, and she managed to fatten me up 20 pounds. •To become fat or fatter by gaining weight.‘And isn’t Declan looking very thin?’ Madge said. ‘He’ll never get a wife if he doesn’t fatten up a bit.’ — 1999 •(figurative) To make bigger; to expand.We must not fatten up our payroll with people performing nonessential activities. — 1954 formsfattening up · fattened up · fattens up