famous last words noun[usually plural]2 •A notable final utterance before death, especially one made by a celebrity or historical figure.Lawrence died defending his vessel and his famous last words, "Don't give up the ship," have been familiar to every schoolboy. — 1908 •(figurative) A statement which is overly optimistic, results from overconfidence, or lacks realistic foresight.Says one Sperry product executive: "As a manager, there is almost nothing you can do to get fired here." Considering the new circumstances, those could be famous last words. — 1986 formsfamous last word