episteme UK /ˌɛp.ɪˈstiː.mi/US /ˌɛp.əˈsti.mi/ noun3 •Scientific knowledge; a principled system of understanding; sometimes contrasted with empiricism. •The fundamental body of ideas and collective presuppositions that defines the nature and sets the bounds of what is accepted as true knowledge in a given epistemic epoch. •Know-how; compare techne. formsepistemai · epistemes · epistemés · epistêmês