down and out adjective 1noun 2forms 2 adjective1 •In a condition of poverty or debility, especially as a result of experiencing a financial or personal setback.People who are down and out need some place to turn. noun2 •Synonym of down-and-outer. •Synonym of down-and-outer.So they have trooped forth to organize village down-and-outs and ne'er-do-wells into would-be combat units. — 1933 formsdown and outs · down-and-outs