dicyclohexylcarbodiimide /ˌdaɪˌsaɪkloʊˈhɛksəlˌkɑːrboʊdaɪˈɪmaɪd/ noun1 •A chemical reagent commonly used in organic synthesis to activate carboxylic acids so they can form bonds with amines, especially to create amide bonds in peptide synthesis. It works as a coupling agent that helps join molecules together, producing dicyclohexylurea as a byproduct. formsdicyclohexylcarbodiimides