descend upon verb4 •To arrive, usually without warning or invitation. •To arrive suddenly or unexpectedly, especially in a manner that causes disruption or inconvenience.My neighbour descended upon me just as I was walking out the door. •To visit in large numbers, especially a public place.This fall, millions of devout Muslims will descend upon Mecca, Medina, and Saudi Arabia's holy sites in one of the largest annual migrations in human history. — 2013 •To make an attack or incursion, from or as if from a vantage ground; to come suddenly and with violence. formsdescended upon · descending upon · descends upon