CPU UK /(ˌ)siː(ˌ)piːˈjuː/US /ˌsi(ˌ)piˈju/ noun4 •(slang) The main computer case containing the central components of a personal computer. •Initialism of central processing unit.Dell has announced that the new XPS 13 and XPS 13 2-in-1 will be its first to feature 11th-Gen Intel CPUs and meet the Evo certification. — 2020 •Any character or entity controlled by the game software. •Initialism of clinical practice unit. formsCPUs