COVID toes noun[plural only]1 •(informal) A PIIRS (“post-inflammatory infectious response syndrome”) associated with COVID-19, affecting mostly children, showing up as reddish or bluish swollen toes or fingers, with blisters or peeling skin.COVID toes usually begin with the patient noticing red or purple discoloration of the toes, and in some cases the skin can become raised or develop ulcerations. — 2020
