cornify UK /ˈkɔː.nɪ.faɪ/US /ˈkɔɹ.nɪ.faɪ/ verb1 •To convert or be converted into horn or a similar substanceNo longer in contact with an inner root sheath, the isthmus epithelium cornifies without a granular zone, and the thin cornified layer is composed of compactly arranged cornified cells. — 1985 formscornified · cornifying · cornifies