chloramphenicol UK /ˌklɔː.ɹamˈfɛ.nɪ.kɒl/US /ˌklɔˌɹæmˈfɛ.nɪˌkɔl/ noun1 •A broad-spectrum antibiotic C₁₁H₁₂Cl₂N₂O₅ isolated from cultures of a soil actinomycete (Streptomyces venezuelae) or prepared synthetically and used against serious infections such as typhoid fever. formschloramphenicols