brain drain noun 2verb 2forms 6 noun2 •The migration of educated or talented people from less economically advanced areas to more economically advanced areas, especially to large cities or more developed nations.Fortunately, the often-discussed problem of "the brain drain" is not as serious in agriculture as in most other fields, particularly the "hard sciences." — 1955 •(informal) A Jackson-Pratt drain. verb2 •Of a nation or society, to be deprived of educated or talented people, who in turn migrate to larger cities or more developed nations. •To become mentally or psychologically fatigued or exhausted. formsbrain drained · brain-drained · brain-draining · brain draining · brain drains · brain-drains