blues and twos adverb 1noun 1 adverb1 •(UK, informal) [of an emergency vehicle] with the blues and twos switched onIf Mondo was alive, he'd be long gone, the ambulance hurtling blues and twos to the nearest hospital. — 2003 noun[plural only]1 •(UK, informal) The flashing lights and loud siren of an emergency vehicle.Five minutes later, Bella, efficient as ever, radioed him back with an address near Hove station, about ten minutes drive away, going soberly, or ninety seconds with the blues and twos on. — 2006