blood brother noun3 •An unrelated male considered to share a brother-like relationship established by a ceremonial sharing of blood in some cultures."He is a blood brother and an oath brother of Odin, highest of the gods." — 2017 •An unrelated male considered to share such a strong relationship generally. •A brother by blood: a brother-german or half-brother, as distinguished from step-brothers. formsblood brethren · blood brothers