best girl noun3 •(Internet, slang) A reader or viewer's preferred female character.Also: Miku is best girl, thank you for attending this TED Talk. — 2020 •(old-fashioned) One's girlfriend.[…] your fine magazine […] is a pleasure to read anywhere, but in an isolated spot such as this it's almost as good as a sugar report from the best girl! — 1954 •A woman who performs the duties of a best boy. formsbest girls