any way one slices it UK /ˌɛni‿weɪ wʌn ˈslaɪsɪz‿ɪt/US /ˌɛni‿weɪ wʌn ˈslaɪsəz‿ət/ phrase1 •(US, informal) From any perspective; in every case.Any way you slice it, we have to get out of here and we have to take him with us.