antisepsis UK /ˌæn.tiˈsɛp.sɪs/US /ˌæn.tɪˈsɛp.sɪs/ noun2 •The science and practice of countering microbial infection, as with the use of antiseptics, and the use of aseptic technique. •(no longer used) Any antiseptic agent. formsantisepses