Antigua and Barbuda UK /ænˌtiː.ɡə ən(d)bɑːˈb(j)uː.də/US /ænˌti.ɡ(w)ə ənd bɑɹˈbju.də/ noun1 •A country consisting of two islands in the Caribbean, Antigua and Barbuda, and numerous other small islands. Largest city: St. John's.