alterative UK /ˈɒl.tɹə.tɪv/US /ˈɔl.tɚˌaɪ.tɪv/adjective 2noun 1forms 3 adjective2 •Causing alteration. •Gradually changing, or tending to change, a morbid state into a healthy one. noun1 •(historical) A medicine or treatment which works by changing processes within the body, rather than by evacuating something etc.Amongst this number of cordials and alteratives I do not find a more present remedy than a cup of wine or strong drink, if it be soberly and opportunely used. — 1624 formsalteratives · more alterative · most alterative