Addison's disease noun1 •A disorder in which the adrenal glands fail to produce a sufficient quantity of steroids, causing hypocortisolemia and a resultant brownish discoloration of the skin.Nearly thirty years before the date of Addison's discovery, his eminent colleague, Dr. Bright, had observed and recorded, in his celebrated 'Reports of Medical Cases,' a case of Addison's disease. — 1875
