acetylcysteine UK /ˌas.ɪ.tʌɪlˈsɪ.stɪ.iːn/US /əˌsi.tl̩ˈsɪ.stəˌin/ noun1 •An acetylated form of the amino acid cysteine (trademark Mucomyst), which is an antioxidant used as a mucolytic agent and in the treatment of paracetamol poisoning.